Home Telephone Location Click to Search
logo
Call us on: +44 (0) 28 9077 3030

Covid-19

In light of  the current outbreak of COVID-19 and the need for continued PCR testing 4titude have a range of plastic PCR plates which are compatible with a variety of platforms for different tests.

The plates are manufactured exclusively within the UK and there is abundant stock . 

Below are the list of platforms, tests and plates which are compatible .

Should you have any requirements please do not hesitate to get in touch. 

 

List of COVID-19 diagnostics Test kits

  1. Thermo Fischer TaqPath COVID-19 Combo Kit
  • Granted emergency use authorization (EUA) by FDA.
  • For use with ABI 7500 Fast Dx real-time PCR
  • Plan to produce ~5M test kits by April. Kits will be shipped across 200 labs in US. According to the American Enterprise Institute, there are enough machines in the U.S. to run around 26,000 tests per day. 
  • Also supplies various master mixes and polymerases for diagnostic testing that have been cited in several publicly available 2019-nCoV real-time PCR protocols.
  • Also developing a multiplexing test that offers a faster time-to-result to further expand laboratory capacity.

 

Kit recommended consumables

4ti Alternatives

KingFisher™ Deepwell 96 Plate 95040450

 

KingFisher™ 96 KF microplate 97002540

 

MicroAmp™ Fast Optical 96-Well Reaction Plate with Barcode, 0.1 mL 4346906

4ti-0912

MicroAmp™ Clear Adhesive Film 4306311

4ti-0500

MicroAmp™ Optical Adhesive Film 4311971 and 4360954

4ti-0560

 

 

 

  1. Roche Cobas SARS-CoV-2 Test (qRT-PCR test)
  • Granted EUA and CE-IVD marked.
  • For use with Roche's fully automated Cobas 6800 and Cobas 8800 systems.
  • Also partnered with Tib-Molbiol to launch three research-use-only assays for the LightCycler 480 high-throughput real-time PCR instrument.

 

Kit recommended consumables

4ti Alternatives

cobas omni Processing Plate 05534917001

 

cobas omni Amplification Plate 05534941001

 

In-built heat sealer

 

PCR Plates for LC 480

4ti-0951, 4ti-0954, 4ti-0955

 

  1. Panther Fusion SARS-CoV-2 assay, Hologic
  • Granted EUA
  • used with Hologic's fully automated, high-throughput molecular diagnostic platform, the Panther Fusion.

 

  1. COVID-19 RT-PCR test, LabCorp
  • Granted EUA
  • For use with QuantStudio 7 Flex Real-Time PCR System (4titude compatible plates - 4ti-0772, 4ti-0912)

 

  1. Quest SARS-CoV-2 RT-PCR (Quest Diagnostics Infectious Disease, Inc.)

 

Kit recommended consumables

4ti Alternatives

MicroAmp™ Fast Optical 96-Well Reaction Plate with Barcode, 0.1 mL 4346906

4ti-0912

MicroAmp™ Optical Adhesive Film 4311971 and 4360954

4ti-0560

 

  1. Lyra SARS-CoV-2 Assay (Quidel Corp.)

 

Kit recommended consumables

4ti Alternatives

MicroAmp™ Fast Optical 96-Well Reaction Plate with Barcode, 0.1 mL 4346906

4ti-0912

MicroAmp™ Optical Adhesive Film 4311971 and 4360954

4ti-0560

 

  1. CDC 2019-nCoV Real-Time RT-PCR Diagnostic Panel
  • Granted emergency use authorization (EUA) that allows the test to be used at all CDC-qualified labs in the US
  • For use with ABI 7500 Fast Dx Real-Time PCR Systems.
  • The CDC will initially distribute 200 test kits to US domestic laboratories and 200 to selected international labs. Each test kit will have enough reagents to test about 700 to 800 patients. Labs will subsequently need to validate the kits according to CLIA guidelines, which is likely to take a few days

Kit recommended consumables

4ti Alternatives

MicroAmp™ Fast Optical 96-Well Reaction Plate with Barcode, 0.1 mL 4346906, 4366932 

4ti-0912

MicroAmp Optical 8-cap Strips (Applied Biosystems; catalog #4323032)

4ti-0751/4ti-0783

 

  1. Opko's BioReference Laboratories
  • In partnership with New York State Department of Health. The test has been validated and is being performed at BioReference.
  • Applied for EUA for diagnostic testing in CLIA Certified high-complexity laboratories.
  • The new US FDA guidance allows high-complexity commercial, academic, and government labs to develop and use SARS-CoV-2 tests. The guidance requires labs to validate their tests, and then to notify FDA. They may then begin using the test, but must also submit a completed EUA request to FDA within 15 days.

 

  1. Becton Dickinson and BioGX -  Submitted a test US FDA for EUA to detect SARS-CoV-2, the virus that causes COVID-19, that runs on the BD Max system

 

  1. BGI, China
  • Test based on real-time fluorescent RT-PCR kit (received emergency authorization from China's National Medical Products Administration)
  • Donated 20,000 kits in Wuhan, China and Hubei Province and provided about 50,000 test kits in total to hospitals and disease control centers in China.
  • In collaboration with Curetis and its subsidiary Ares Genetics to develop a sequencing-based test and to distribute BGI's PCR-based test in Europe.

 

  1. Amoy Diagnostics (Xiamen, China) — developed a PCR-based test kit and has entered the NMPA emergency approval channel.
  1. Altona Diagnostics (Hamburg, Germany) — developing a real-time RT-PCR based assay for the qualitative detection of 2019-nCoV RNA in respiratory samples.
  1. Biomeme (Philadelphia) — tests called 2019-nCoV Go-Strips that run on Biomeme's mobile handheld qPCR devices are available on the firm's website. The test contains coronavirus RNA target multiplexed with Biomeme's RNA extraction and RT-PCR control (MS2), with each order containing 10 individually packaged Go-Strips that are shelf-stable for up to two years
  1. Bioneer (Daejeon, Korea) — submitted a diagnostic test kit for emergency use assessment and listing (EUAL) to the Korea Centers for Disease Control and Prevention (KCDC).
  1. CerTest (Zaragoza, Spain) — developing a test kit called VIASURE 2019-nCoV Real Time PCR Kit, based on its existing qPCR tests for other coronaviruses.
  1. Center for Convergent Research of Emerging Virus Infection (CEVI) at the Korea Research Institute of Chemical Technology and Wells Bio (Seoul, Korea) — pursuing joint development and commercialization of molecular and immunological diagnostics to detect a 2019-nCoV gene and a viral antigen.
  1. Columbia University (New York City) — the lab of Ian Lipkin is reportedly developing a test to detect and differentiate 2019-nCov from influenza.
  1. Coyote Bioscience (Beijing) — has reportedly submitted its one-hour, sample-to-answer 2019-nCoV Prep Free QPCR Assay to NMPA for emergency authorization. It runs on the firm's CFDA-approved Mini8 Portable Molecular Diagnostic QPCR Station. The test is reportedly being used as an RUO in China in more than 30 hospitals, 16 local CDC offices, and eight airports, and the firm has donated 500 instruments to Hubei province.
  1. GeneFirst (Oxford, UK) — developing two test kits; a three-hour PCR-based test for 2019-nCoV, and a multiplex PCR assay for 2019-nCoV as well as 17 other common viruses and bacteria.
  1. Genekam Biotechnology (Duisburg, Germany) — developed singleplex and multiplex test kits to detect 2019-nCoV as well as to distinguish it from other infections, such as influenza, MERS, and viruses commonly found in bats.
  1. Genomica (Madrid) — developing a 2019-nCoV diagnostic kit to simultaneously analyze 96 patient samples in less than five hours, to be available in five to seven weeks, using the firm's low-density microarray-based platform. Genomica has also had a subsidiary in Wuhan, China, named HuaSin Science, since January 2018.
  1. GenScript (Piscataway, New Jersey) — has launched a one-step 2019-nCoV quantitative reverse-transcription polymerase chain reaction (RT-qPCR) based on the World Health Organization's protocol. The firm is also marketing plasmids encoding the surface glycoprotein and nucleocapsid phosphoprotein of 2019-nCoV that can be used as positive control for the detection of 2019-nCoV by RT-PCR.
  1. IDbyDNA (Salt Lake City, Utah)
  • Validated LDT
  • the firm's Explify Respiratory test uses next-generation sequencing-based metagenomics to detect 2019-nCoV as well as over 900 other viral, bacterial, fungal, and parasitic pathogens.
  • Also collaborated with illumine to develop NGS panes for infectious disease applications.

 

  1. Kogene Biotech (Seoul, Korea) — submitted a diagnostic test kit to the KCDC for EUAL.
  1. LabGenomics (Seoul, Korea) — developing a kit and anticipates commercialization in the next two months.
  1. Lexagene (Beverly, Massachusetts) — developing a test for its one-hour, open-access LX Analyzer system.
  1. Novacyt (Paris and Camberley, UK) — the firm's molecular diagnostics division, Primerdesign, has launched a two-hour molecular test, available as an RUO test, designed to run on multiple molecular testing platforms, including Primerdesign's genesig q16 and q32 instruments.
  1. PCL (Seoul, Korea) — in the process of commercializing its multiplex diagnostic kit.
  1. TCM Biosciences (Seoul, Korea) — developing a test called TCM-Q Corona III.
  1. University of Hong Kong (Hong Kong) — researchers have developed two single-step quantitative real-time reverse-transcription PCR assays to detect two different regions of the viral genome, as described in a recent Clinical Chemistry study.
  1. Integrated DNA Technologies (Coralville, Iowa) —qPCR primers and probes designed to detect 2019-nCoV
  1. LGC (Milford, Massachusetts)
  • Developed reference materials (SeraCare Life Sciences subsidiary)
  • Biosearch Technologies subsidiary is also expediting availability of its as Black Hole and Blackberry Quenchers (BHQ and BBQ) and other dyes and components used in diagnostic kits, as these are explicitly mentioned in the publication describing the primer and probe sequences recommended for 2019-nCoV diagnosis.
  1. Longhorn Vaccines and Diagnostics (Bethesda, Maryland)
  • the firm has announced its PrimeStore MTM collection medium is the first and only device that is validated for coronavirus and that the FDA created a new category for it: FDA Cleared: New Class II Predicate Device Oral and Nasopharyngeal swab screening.
  1. Meridian Bioscience (Cincinnati, Ohio) —freeze-dried Lyo-Ready 1-Step RT q-PCR mix (already in use in China)
  1. Co-Diagnostics
  1. Novacyt's, France
  1. Atila Biosystems - developing a test using its high-throughput isothermal nucleic acid amplification system.

 

Sign up to our monthly Promotions Letter